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本文用补体依赖微量细胞毒方法测定了473例青年、儿童、老年、妊娠妇女、妊娠中毒症患者、SLE患者的B淋巴细胞冷抗体,其中一部份标本还测定了免疫复合物。类风湿因子(RF),HLA抗体及冷球蛋白,并分别比较它们之间的相互关系。结果显示B淋巴细胞冷抗体在自身抗体较高的老年、妊毒症、SLE三组中检出率最高,提示可能它的产生与机体自身抗体及自身免疫现象有关。在妊娠妇女中冷抗体与HLA抗体常同时出现,显示了二者的相关性。
In this study, cold-antibody B lymphocytes from 473 young, children, pregnant women, pregnant patients with gestational toxicosis and SLE were measured by complement-dependent microcytotoxicity assay. Some immune complexes were also assayed in some of them. Rheumatoid factor (RF), HLA antibodies and cryoglobulins, and compare their correlations. The results showed that B lymphocytes cold antibodies in the elderly high autoantibodies, pregnancy-induced sepsis, SLE three groups detected the highest rate, suggesting that its possible production and autoantibodies and autoimmune phenomenon. In pregnant women in cold antibodies and HLA antibodies often appear at the same time, showing the correlation between the two.