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目的:探讨邻苯二甲醛的模拟现场消毒效果,并对其连续使用的稳定性进行评价。方法:使用载体定量杀菌试验和模拟消毒试验方法,对邻苯二甲醛与戊二醛消毒内镜的效果和连续使用稳定性进行比较。结果:全自动清洗消毒机模拟现场试验结果显示,邻苯二甲醛灭菌消除率与戊二醛灭菌消除率相比,差异具有统计学意义(P<0.05);手工操作模拟现场试验结果显示,邻苯二甲醛对枯草杆菌的消除率显著高于戊二醛(P<0.05);连续使用稳定性结果显示,邻苯二甲醛连续使用后的浓度降低百分比明显低于戊二醛(P<0.05);连续使用后邻苯二甲醛的灭菌消除率显著高于戊二醛(P<0.05)。结论:邻苯二甲醛在模拟现场条件下,无论消毒机处理还是手工处理消毒效果均优于戊二醛,连续使用后仍能保持在有效浓度范围内,且连续使用稳定性优于戊二醛,值得临床进一步推广使用。
Objective: To explore the simulated field disinfection effect of o-phthalaldehyde and to evaluate the stability of its continuous use. Methods: The quantitative sterilizing test and simulated disinfection test were used to compare the efficacy and the stability of continuous use of o-phthalaldehyde and glutaraldehyde disinfection endoscopy. Results: The field test results of automatic cleaning and disinfecting machine showed that the difference between the rate of elimination of ortho-phthalaldehyde and the rate of elimination of glutaraldehyde was statistically significant (P <0.05). The results of manual field simulation (P <0.05). The results of continuous use stability showed that the decreasing percentage of phthalaldehyde after continuous use was significantly lower than that of glutaraldehyde (P < 0.05). The sterilization rate of phthalaldehyde after continuous use was significantly higher than that of glutaraldehyde (P <0.05). CONCLUSION: Orthophthalaldehyde is better than glutaraldehyde in disinfecting machine or hand-treating disinfection under simulated field conditions, and can be kept within the effective concentration range after continuous use, and its continuous use stability is better than that of glutaraldehyde , It is worth to further promote the use of clinical.