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目的:探讨宫颈细胞学检查中意义不明确的不典型鳞状上皮细胞(ASCUS)的组织病理学结果及临床管理措施。方法:回顾性分析2006年2月~2008年11月威海市妇女儿童医院妇科门诊细胞学检查16 414例中诊治随访的、细胞学检查报告为ASCUS的患者675例,在阴道镜下取活检494例。结果:494例患者中,288例为炎症(58.3%)、169例为轻度不典型增生(34.2%)、9例为中度不典型增生(1.8%)、14例为重度不典型增生(2.8%)、2例为宫颈原位癌(0.4%)、2例宫颈浸润癌(0.4%)。结论:在细胞学检查为ASCUS的患者中,其组织病理学检查结果显示有一定比例的宫颈上皮内瘤变和宫颈癌,应重视对ASCUS的评价与临床管理。
Objective: To investigate the histopathological findings and clinical management of atypical squamous cells (ASCUS) with undefined significance in cervical cytology. Methods: A retrospective analysis of 16 414 cases of cytology in gynecological clinic of Weihai Women and Children Hospital from February 2006 to November 2008 was retrospectively reviewed, and 675 cases of cytology were reported as ASCUS. Surgical examination was performed under colposcopy 494 example. RESULTS: Among the 494 patients, 288 were inflammation (58.3%), 169 were mild dysplasia (34.2%), 9 were moderate dysplasia (1.8%) and 14 were severe dysplasia 2.8%), 2 cases of cervical carcinoma in situ (0.4%) and 2 cases of invasive cervical carcinoma (0.4%). Conclusion: In the cytology ASCUS patients, the results of histopathological examination showed a certain proportion of cervical intraepithelial neoplasia and cervical cancer, should pay attention to the evaluation and clinical management of ASCUS.