作者报告由于不同抗菌素引起反复急性肾功能衰竭1例。患者男性,66岁。入院前4个月,因反复泌尿道感染作膀胱镜检查,其后因败血症曾用多个疗程的复方新钠明(Co-trimoxazole)、氨苄青霉素、头孢力新和奈啶酸。病前肾功能正常。住院时患者正在服复方新纳明。血象正常,血尿素426mg％,血清肌酐15.9mg％。尿培养阴性,有大量红,白细胞,尿量60ml/h,即进行腹膜透析。肾活检后,予强地松龙1.0g/日静点连续2天,72小时后,尿量140ml/h。其后恢复顺利。1个月后肌酐清除率60ml/min,患者感不适、发热(38.9℃),尿培养 The authors report 1 case of recurrent acute renal failure due to different antibiotics. Patient male, 66 years old. Four months prior to admission, cystoscopy was performed due to recurrent urinary tract infections. Co-trimoxazole, ampicillin, cefotaxime and nalidixic acid were used for multiple courses of sepsis. Pre-sick kidney function is normal. Patients are taking compound neminamine when hospitalized. Blood was normal, blood urea 426mg%, serum creatinine 15.9mg%. Negative urine culture, a large number of red, white blood cells, urine output 60ml / h, that peritoneal dialysis. After renal biopsy, prednisolone 1.0g / day for 2 consecutive days, 72 hours after the urine output 140ml / h. Then resume smoothly. 1 month after the creatinine clearance rate of 60ml / min, patients with discomfort, fever (38.9 ℃), urine culture