论文部分内容阅读
目的探讨脑利钠肽(BNP)对无症状心力衰竭的诊断价值。方法使用微粒子免疫定量检测法,检测132例无症状的CHD患者血浆BNP水平并行超声心动图、心功能检测,进行比较分析。并于治疗后2周检测102例CHF患者血浆BNP水平。结果 132例CHD患者中BNP异常有102例(83.61%),其中超声心动图异常的92例,占90.18%。血浆BNP水平与LVEF呈负相关性(P<0.05)。治疗后2周BNP水平下降,而LVEF水平升高,与治疗前比较差异有统计学意义(P<0.05)。结论 BNP监测提高了无症状心衰的检出率,可作为较可靠的CHF早期诊断参考指标,对CHF严重程度和疗效以及预测预后具有重要意义。
Objective To investigate the diagnostic value of brain natriuretic peptide (BNP) in asymptomatic heart failure. Methods The quantitative BNP level was measured in 132 asymptomatic CHD patients by echocardiography and heart function test. Plasma BNP level was measured in 102 CHF patients two weeks after treatment. Results 132 cases of abnormal BNP in 132 CHD patients (83.61%), of which 92 cases of abnormal echocardiography, accounting for 90.18%. Plasma BNP levels were negatively correlated with LVEF (P <0.05). BNP level decreased 2 weeks after treatment, while LVEF level increased, compared with before treatment, the difference was statistically significant (P <0.05). Conclusion BNP monitoring can improve the detection rate of asymptomatic heart failure, which can be used as a more reliable reference index for early diagnosis of CHF, and is of great significance for the severity and efficacy of CHF and prognosis.