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目的了解医院感染大肠埃希菌分布及其耐药性情况,为临床合理使用抗菌药物提供依据。方法采用回顾性调查方法,对某医院2010-2011年住院病人送检标本检测结果进行了统计分析。结果临床分离大肠埃希菌对亚胺培南、头孢他定、阿米卡星和氨曲南等抗菌药物的敏感率仍保持在71%以上,对其他常用抗菌药物普遍耐药。结论临床分离大肠埃希菌对常用抗菌药物耐药比较普遍,并产生多重耐药,应严格控制抗菌药物的使用指征。
Objective To understand the distribution and drug resistance of Escherichia coli in hospital and provide a basis for rational use of antibacterials in clinical practice. Methods A retrospective survey method was used to analyze the test results of inpatients from 2010 to 2011 in a hospital. Results The sensitivity of clinical isolates of Escherichia coli to imipenem, ceftazidime, amikacin and aztreonam remained above 71%, which was generally resistant to other commonly used antibiotics. Conclusion Clinical isolates of Escherichia coli commonly used antimicrobial resistance is more common, and produce multiple drug resistance, antibiotic indications should be strictly controlled.