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目的:分析度洛西汀治疗慢性阻塞性肺疾病(COPD)患者抑郁焦虑症状的疗效。方法采用行抑郁自评量表(SDS)、汉密顿抑郁量表(HAMD)及汉密尔顿焦虑量表(HAMA)测量患者心理状况,将92例慢性阻塞性肺疾病患者中,53例抑郁症患者和42例焦虑症患者分别随机分为观察组和对照组,对照组患者进行常规治疗,观察组患者进行常规治疗的基础上,加服度洛西汀治疗。连续服药4w后,对患者进行调查分析并记录药物反应情况。结果观察组和对照组连续服药4w后,观察组患者的抑郁焦虑症状有明显改善,其中会出现恶心、头疼、口干、失眠等不良反应,情况较严重者进行辅助治疗,治疗后没有新的异常。结论度洛西汀可以有效改善慢性阻塞性肺疾病患者的抑郁焦虑症状,提升患者的生活质量。“,”Objective:to analysis of duloxetine in the treatment of chronic obstructive pulmonary disease (COPD) patients with depression and anxiety. Methods: a line of self rating Depression Scale (SDS), Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale (HAMA) measurement of psychological status of the patients, 92 cases of chronic obstructive pulmonary disease were randomly divided into the observation group and the control group, the control group were treated with routine treatment, the observation group were treated with routine basis treatment, and taking duloxetine treatment. After 4 weeks of continuous medication, were investigated and recorded drug reactions of two groups of patients. Results: after 4 weeks, the observation group and the control group to observe the continuous medication, depression and anxiety group were significantly improved, the adverse reaction of nausea, headache, dry mouth, insomnia, the situation is more serious for adjuvant treatment, after treatment, no new anomaly. Conclusion: duloxetine can ef ectively improve the patients with chronic obstructive pulmonary disease symptoms of anxiety and depression, improve the quality of life of the patients.