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作者评价以5～10%常规剂量的链激酶直接注入患侧肺动脉,联合静脉注射肝素治疗急性肺血栓栓塞的效果以及这种疗法的可能危险。材料和方法经血管造影证实的急性大块肺栓塞病人7例,男4例,女3例,年龄45～73岁。4例有休克或昏厥,1例有肺梗塞,咯血和/或胸膜性胸痛,3例有呼吸困难。症状出现至使用肝素和链激酶时间6例少于72h,1例约为96h。治疗前全部病例均行通气-灌注扫描以作对照,治疗开始后12～24h
The authors evaluate the efficacy of injecting heparin directly into the affected side of the pulmonary artery with streptokinase at a conventional dose of 5 to 10% in combination with intravenous heparin to treat acute pulmonary thromboembolism and the possible risk of this regimen. Materials and Methods 7 cases of acute pulmonary embolism confirmed by angiography, 4 males and 3 females, aged 45 to 73 years old. 4 had shock or fainting, 1 had pulmonary infarction, hemoptysis, and / or pleural chest pain and 3 had dyspnea. Symptoms appear to use heparin and streptokinase in 6 cases less than 72h, 1 case was about 96h. All cases before treatment were ventilated - perfusion scan as a control, 12 ~ 24h after the start of treatment