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[目的]观察益胃汤联合西药三联法治疗幽门螺杆菌相关胃炎疗效。[方法]使用随机平行对照方法,将76例门诊患者按就诊顺序号抽签、病志号抽签方法简单随机分为两组。对照组38例三联治疗,克拉霉素,500mg/次,2次/d,口服;奥美拉唑,40mg/次,1次/d,口服;阿莫西林,500mg/次,2次/d,口服。治疗组38例益胃汤,炙甘草、三七粉分两次吞、黄连各6g,枳实、柴胡、玄胡索、川楝子、浙贝母、制半夏、陈皮各10g,党参、丹参、蒲公英、乌贼骨各15g,白芨、谷麦芽各20g,白芍24g,大枣5枚,生姜3片,1剂/d,水煎450m L,早晚口服;西药治疗同对照组。连续治疗1周为1疗程。观测临床症状、症状学积分、病理学积分、不良反应。连续治疗4疗程,判定疗效。[结果]治疗组痊愈15例,显效13例,有效8例,无效3例,总有效率94.74%。对照组痊愈10例,显效10例,有效7例,无效11例,总有效率71.05%。治疗组疗效优于对照组(P<0.01)。症状学积分、病理学积分改善治疗组治疗组优于对照组(P<0.05)。[结论]益胃汤联合西药三联法治疗幽门螺杆菌相关胃炎,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the therapeutic effect of Yisweitang combined with western medicine triple therapy on Helicobacter pylori associated gastritis. [Methods] Using randomized parallel control method, 76 outpatients were randomly selected according to the sequence number of visiting doctor. The control group of 38 patients triple therapy, clarithromycin, 500mg / time, 2 times / d, omeprazole, 40mg / time, 1 / d, orally; amoxicillin, 500mg / time, 2 times / d ,oral. The treatment group 38 cases of Yiwei Tang, Zhigancao, notoginseng powder twice swallow, Coptis 6g, citrus aurantium, Bupleurum, Xuan Hu Suo, Toosendan, Fritillaria, Pinellia, dried tangerine peel 10g, Codonopsis , Radix Salviae Miltiorrhizae, dandelion and squid bones, each with 15g, Baiji, Valley malt each 20g, white peony root 24g, jujube 5, ginger 3, 1 agent / d, decoction 450m L, morning and evening oral; Western medicine treatment with the control group. Continuous treatment for 1 week for a course of treatment. Observed clinical symptoms, symptom scores, pathology scores, adverse reactions. Continuous treatment of 4 courses to determine the efficacy. [Result] The treatment group cured 15 cases, markedly effective in 13 cases, effective in 8 cases, ineffective in 3 cases, the total effective rate was 94.74%. The control group recovered 10 cases, markedly effective in 10 cases, effective in 7 cases, ineffective in 11 cases, the total effective rate was 71.05%. The treatment group than the control group (P <0.01). The scores of symptomology and pathology were better in the treatment group than in the control group (P <0.05). [Conclusion] Yiwei Decoction combined with western medicine triple therapy for Helicobacter pylori associated gastritis has satisfactory curative effect and no serious adverse reactions, which deserves promotion.