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颞动脉炎(TA)主要发生于老年人,在此特殊性肉芽肿性全动脉炎者中约有半数病人有眼部体征。其眼部体征发生率各学者报告不一,高者达40%;常见的眼部体征(占所报导病例的90%以上)为缺血性视神经病变,认为是由于睫状后短动脉供血不足所致。Francois称为“苍白性视乳头水肿”或“血管性假性视乳头炎”,认为是由于病变波及视神经的中央动脉所致。晚近对此病的发病机理作了研究,指出TA的发病属于自身免疫学机制,业已证明TA患者动脉壁有免疫球蛋白及补体成分的沉积。本文通过15例具有眼部体征的TA病人观察发现:在这些病人血清中有循环免疫复合物(ClCs)及抗核抗体(ANAs),并作了血清内IgG、IgA、IgM及补体成分C_3与C_4的测定。15例(女性12例,男3例,平均年
Temporal arteritis (TA) occurs mainly in the elderly, in which about half of all patients with granulomatous arteritis have ocular signs. The incidence of ocular signs of various scholars reported different, up to 40%; common eye signs (accounting for more than 90% of reported cases) for ischemic optic neuropathy, that is due to short ciliary artery insufficiency Due. Francois called “pale papilledema” or “vasopagitis” is thought to be due to lesions affecting the optic nerve central artery. The pathogenesis of this disease has recently been studied, pointed out that the pathogenesis of TA belong to the mechanism of autoimmune, has been shown in patients with TA TA wall immunoglobulin and complement components of the deposition. In this paper, 15 cases of TA patients with ocular signs were observed: in these patients serum circulating immune complexes (ClCs) and antinuclear antibodies (ANAs), and serum IgG, IgA, IgM and complement components C_3 C_4 determination. 15 cases (12 females, 3 males, mean years