前文指出,SC1001钠盐对中枢神经活动有抑制作用。某些镇静催眠药常有抗惊厥作用,而惊厥是癫痫的主要症状。本工作是观察SC1001钠盐有无抗惊厥作用。选用体重1.7～2.5kg健康雄性家兔34只,随机分成Ⅰ、Ⅱ、Ⅲ、Ⅳ组。Ⅱ、Ⅲ、Ⅳ组分别为10、10、5只,在腹腔注射SC1001(注射剂量分别为100、200和300mg/kg)后30分钟,肌肉注射马桑内酯3mg/kg。Ⅰ组(9只)肌注相同剂量的马桑内酯作为对照。分别观 The previous article pointed out that SC1001 sodium salt has inhibitory effects on central nervous activity. Certain sedative hypnotics often have anticonvulsant effects, and seizures are the main symptoms of epilepsy. This work is to observe whether SC1001 sodium salt has anticonvulsant effect. Thirty-four healthy male rabbits weighing 1.7 to 2.5 kg were randomly divided into groups I, II, III and IV. In Groups II, III, and IV, 10, 10, and 5 mice were given intramuscular injections of 3 mg/kg of coriaria lactone 30 minutes after intraperitoneal injection of SC1001 (100, 200, and 300 mg/kg, respectively). Group I (nine mice) received intramuscular injection of the same dose of coriaria lactone as a control. Separate views