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目的 研究肺癌全肺切除的术后并发症及其与临床危险因素的关系。方法 对 2 4 1例接受全肺切除的肺癌患者进行分析 ,统计术后并发症的发生情况及其临床危险因素。结果 术后 30d内 6 3例 (2 6 1% )发生并发症 ,死亡 10例 (4 1% )。通过单因素和多因素分析 ,年龄、术前FEF5 0 %、MVV %、FEV1 0 %及手术部分的OR值分别为5 97、 5 98、 5 2 1、 3 2 8、 2 5 2 (P <0 0 5 )。结论 全肺切除术后并发症的发生率及病死率均较高。年龄≥ 6 0岁、术前FEF5 0 %、MVV %、FEV1 0 %低于正常的 80 %、右全肺切除是导致全肺切除术后并发症发生的危险因素
Objective To study the postoperative complications of pneumonectomy and its relationship with clinical risk factors. Methods Totally 214 cases of lung cancer undergoing total pneumonectomy were analyzed. The incidence of postoperative complications and its clinical risk factors were analyzed. Results Sixty-three patients (261%) developed complications within 30 days after operation, and 10 patients died (41%). According to univariate and multivariate analysis, the age, preoperative FEF50%, MVV%, FEV1% and OR of the operative part were respectively 5 97, 5 98, 521, 32 8 2 5 2 (P < 0 0 5). Conclusion The incidence of postoperative pneumonectomy complications and mortality are higher. Age ≥ 60 years, preoperative FEF5 0%, MVV%, FEV1 0% lower than the normal 80%, right pneumonectomy is a risk factor leading to postoperative pneumonectomy complications