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目的比较国产阿卡波糖胶囊剂与进口片剂治疗2型糖尿病的经济效果。方法采用药物经济学原理对2种方案进行成本-效果分析。结果与治疗前比较,用药4wk及8wk后2组空腹血糖(FBG)及餐后血糖(2hPBG)水平均下降(P>005);用药8wk后2组糖化血红蛋白(HbA1c)均有明显下降(P<005)。治疗组成本-效果比低于对照组。结论国产阿卡波糖胶囊剂治疗2型糖尿病的疗效与其进口片剂相当,但经济效果优于进口片剂。
Objective To compare the economic effects of domestic acarbose capsules and imported tablets in the treatment of type 2 diabetes mellitus. Methods Based on the principles of pharmacoeconomics, cost-effectiveness analysis was carried out on two kinds of schemes. Results Compared with those before treatment, fasting blood glucose (FBG) and postprandial blood glucose (2hPBG) in both groups decreased after 4wk and 8wk treatment (P> 0.05), and decreased significantly after 8wk treatment (P <005). The cost-benefit ratio of the treatment group was lower than that of the control group. Conclusion The efficacy of domestic acarbose capsules in treating type 2 diabetes is comparable to that of imported tablets, but the economic effect is better than that of imported tablets.