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目的:探讨分析腺苷脱氨酶(ADA)、C反应蛋白(CRP)、癌胚抗原(CEA)在胸腔积液诊断中的意义。方法:从2011年1月至2014年1月来院就诊的胸腔积液患者中选取108例,其中恶性20例,结核性58例,炎性30例。根据不同性质的胸腔积液对患者进行分组,即恶性组、结核组和炎性组。对其临床资料进行回顾性分析,分析比较ADA、CRP、CEA三个指标的水平。结果:ADA、CRP在恶性组中无明显变化,但在炎性组以及结核组中的水平升高较为明显,和恶性组比较差异具有统计学意义(P<0.05);CEA在结核组和炎性组中变化不明显,而在恶性组中水平明显升高,与结核组和炎性组比较,差异具有统计学意义(P<0.05)。结论:ADA、CRP、CEA综合检测对于临床鉴别诊断胸腔积液意义重大,具有较高的临床价值。
Objective: To investigate the significance of the diagnosis of pleural effusion by analyzing the expression of ADA, CRP and CEA. Methods: From January 2011 to January 2014, 108 patients with pleural effusion were included in this study, including 20 malignant cases, 58 tuberculous cases and 30 inflammatory cases. According to different types of pleural effusion patients were grouped, namely malignant group, tuberculosis group and inflammatory group. Retrospective analysis of its clinical data, analysis and comparison of ADA, CRP, CEA three indicators of the level. Results: ADA and CRP had no significant change in malignant group, but the level of ADA and tuberculosis in inflammatory group and tuberculosis group was significantly higher than that in malignant group (P <0.05); CEA in tuberculosis group and inflammation There was no obvious change in the sex group, but the level in the malignant group was significantly higher than that in the tuberculosis group and the inflammatory group (P <0.05). Conclusion: The combined detection of ADA, CRP and CEA has great clinical significance for the differential diagnosis of pleural effusion.