为了调查儿童残伤状况和病因，从92年-96年对儿科遗传咨询门诊680例患儿，进行系统全面检查的结果，发现83例残疾儿，其中遗传性疾病及先天缺陷占45例，原因不明的占28例，后天疾病致残者10例．说明儿童致残性疾病发病率约12．2％，严重影响了人口素质．特别强调指出氨基糖甙类抗生素的耳毒性已成为听力语言残疾的主要因素．儿童致残疾病的研究是值得十分关注的领域． In order to investigate the status and cause of children’s residual injury, from a systematic and comprehensive examination of 680 pediatric genetic counseling clinics from 1992 to 1996, 83 children with disabilities were identified, of which 45 were genetic diseases and birth defects. Unknown accounted for 28 cases, acquired disease 10 cases of disability. This shows that the incidence of disabling disabled children is about 12.2%, seriously affecting the quality of the population. Special emphasis was placed on the ototoxicity of aminoglycoside antibiotics as a major cause of hearing impairment. Research on disability in children is an area of ​​considerable concern.