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目的:探讨重度子痫前期并发胎盘早剥的临床特征及妊娠结局。方法:对深圳市光明新区人民医院2010~2012年收治85例重度子痫前期患者10例合并胎盘早剥为观察组,75例未合并胎盘早剥为对照组。结果:两组患者在年龄、体重指数、发病孕周、产次、产前最高收缩压对比差异无统计学意义(P>0.05);观察组患者在产前最高舒张压、24 h尿蛋白定量、血清白蛋白、重度水肿、产前阴道流血、眼底小动脉出血、胎儿窘迫均高于对照组,差异有统计学意义(P<0.05);新生儿窒息、新生儿死亡、产后出血、DIC、胎盘卒中、子宫切除均高于对照组,差异有统计学意义(P<0.05)。结论:胎盘早剥是重度子痫前期患者严重的并发症,在治疗早期应重视患者临床表现,同时监测病情变化,结合B超检查对患者早诊断、早治疗,可以有效提高母婴预后。
Objective: To investigate the clinical characteristics and pregnancy outcome of severe preeclampsia complicated with placental abruption. Methods: From 2010 to 2012, 85 cases of severe preeclampsia were treated in Guangming New District People’s Hospital of Shenzhen City. Ten patients with placental abruption were treated as observation group and 75 patients without placental abruption as control group. Results: There was no significant difference in the highest systolic blood pressure between the two groups in age, body mass index, gestational gestational age, parity and prenatal (P> 0.05). In the observation group, the highest prenatal diastolic blood pressure, , Serum albumin, severe edema, prenatal vaginal bleeding, fundus arteriolar bleeding, fetal distress were higher than the control group, the difference was statistically significant (P <0.05); neonatal asphyxia, neonatal death, postpartum hemorrhage, DIC, Placental stroke, hysterectomy were higher than the control group, the difference was statistically significant (P <0.05). Conclusion: Placental abruption is a severe complication of severe preeclampsia. Early treatment should pay attention to the clinical manifestations of the patients and monitor the changes of the disease. Combined with B-ultrasound, early diagnosis and early treatment of the patients can effectively improve the prognosis of the pregnant women.