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本实验从粘附、聚集和释放三方面系统观察了家免失血性休克早期血小板功能的变化、结果表明:休克早期血小板功能显著增强。粘附率、聚集率、血5-羟色胺(5-HT)和血栓素B_2(TXB_2)水平显著升高。随休克时间延长,粘附和聚集逐渐抑制,而5-HT和TXB_2水平进行性升高、提示血小板释放的5-HT和TXA_2是参与失血性休克发展的重要体液因素。
The experiment systematically observed the changes of platelet function in early stage of hemorrhagic shock from the aspects of adhesion, aggregation and release. The results showed that platelet function in early stage of shock was significantly enhanced. Adherence rate, aggregation rate, serotonin (5-HT) and thromboxane B 2 (TXB 2) levels were significantly increased. With the extension of shock time, the adhesion and aggregation gradually inhibited, while the levels of 5-HT and TXB_2 increased progressively, suggesting that 5-HT and TXA_2 released from platelets are important humoral factors involved in the development of hemorrhagic shock.