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目的 探讨神经性厌食症患者的抑制控制功能和正常人群之间的差异.方法 采用病例-对照的研究方法,收集门诊的神经性厌食症患者47名及年龄、性别、受教育年限相匹配的健康对照43名,进行包括Barratt冲动量表在内的一般心理评估,选用信号停止任务(Stop Signal Task)作为评估抑制控制功能的行为学范式,比较两组的差异.结果 1.Barratt冲动量表:患者组量表总分[(66.40±8.72)分]和三个子量表评分[注意冲动性(13.15±2.52)分、行为冲动性(18.34±2.71)分和无计划冲动性(24.26±4.44)分],较正常对照组[分别为(65.49±8.72)分、(13.14±2.60)分、(19.02±3.32)分、(23.14±3.97)分],均差异无统计学意义(P＞0.05).2.行为学测试:AN组的SSRT值[340.66±54.70)ms],较正常对照组[363.55±39.08)ms]明显减低,差异具有统计学意义(P=0.033),提示AN组抑制效率高于正常对照.结论 神经性厌食症患者存在抑制控制功能缺陷,表现为过度抑制.“,”Objective To investigate the differences in inhibitory control function between patients with anorexia nervosa (AN) and healthy controls.Methods A case-control study was utilized in this research.47 patients with AN and 43 matched healthy-control (HC) were included in this study.Information about function of inhibitory control was gathered by means of self-reported inventory including Barratt Impulsiveness Scale (BIS) and a behavioral measure named Stop Signal Task.Results 1.Self-reported inventory of BIS:there was no significant difference between AN and HC in BIS total score ((66.40± 8.72) vs (65.49± 8.72)) and subscale (Attentional imp.(13.15±2.52) vs (13.14±2.60),Motor imp.(18.34±2.71) vs (19.02±3.32),Non-planning imp.(24.26± 4.44) vs (23.14±3.97)) (P＞0.05).2.In behavioral measures,AN group showed significantly decreased in SSRT score((340.66±54.70) ms vs (363.55±39.08) ms,P=0.033),indicating that patients with AN had more efficient inhibitory control.Conclusion AN is characterized by hyperfunction of inhibitory control.