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目的探究经阴道三维超声造影对宫腔内良恶性病变及其与微血管密度的临床应用。方法 80例患者均通过手术获得组织病理学结果,分为良性组(42例)、交界性组(12例)和恶性变组(26例),经阴道三维超声造影检测患者病情,分析该方法对宫腔内良恶性病变及其与微血管密度的诊断价值。结果良性组、交界性组、恶性组的达峰时间、增强强度、AUC值、MVD分别为(16.12±2.08)s、(13.56±1.32)d B、(1 453.96±87.24)d B.s、(14.56±7.12);(14.92±1.63)s、(14.29±1.96)d B、(1 501.38±81.82)d B.s、(21.76±7.28);(13.51±1.42)s、(14.96±2.02)d B、(1 552.13±79.44)d B.s、(37.42±18.53)。结论经阴道三维超声造影可显著区分恶性病变、交界性病变和良性病变,达峰时间和MVD水平是鉴别宫腔内良恶性病变的较好指标。
Objective To investigate the clinical application of transvaginal three-dimensional contrast-enhanced ultrasound in the detection of benign and malignant lesions in uterine cavity and its relationship with microvessel density. Methods Eighty patients underwent histopathological examination. The patients were divided into benign group (n = 42), borderline group (n = 12) and malignant group (n = 26). Transvaginal three-dimensional contrast- Diagnostic value of intrauterine benign and malignant lesions and microvessel density. Results The peak time, intensity, AUC and MVD of benign group, borderline group and malignant group were (16.12 ± 2.08) s, (13.56 ± 1.32) d B, (1453.96 ± 87.24) d Bs, (14.56 ± 7.12); (14.92 ± 1.63) s, (14.29 ± 1.96) d B, (1 501.38 ± 81.82) d Bs, (21.76 ± 7.28); (13.51 ± 1.42) s, (14.96 ± 2.02) d B, 1 552.13 ± 79.44) d Bs, (37.42 ± 18.53). Conclusion Transvaginal three-dimensional contrast-enhanced ultrasound can distinguish malignant lesions, borderline lesions and benign lesions, and the peak time and MVD level are good indicators for differentiating benign and malignant lesions in uterine cavity.