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目的:了解肺癌患者血浆中D-二聚体的水平及临床应用。方法:用EL ISA定量快速检测法测定86例肺癌患者及40例健康体检者血浆D-二聚体水平。结果:肺癌(Ⅰ、Ⅱ、Ⅲa期)及(Ⅲb、Ⅳ期)患者的D-二聚体水平显著高于正常对照组(P<0.01);同时发现肺癌(Ⅲb、Ⅳ期)患者D-二聚体水平也明显高于肺癌(Ⅰ、Ⅱ、Ⅲa期)患者(P<0.01)。结论:血浆D-二聚体水平测定在肺癌肿瘤诊断及病情评估上具有一定的临床意义。
Objective: To understand the plasma level of D-dimer in patients with lung cancer and its clinical application. Methods: The plasma levels of D-dimer in 86 patients with lung cancer and 40 healthy controls were determined by ELISA quantitative rapid test. Results: The levels of D-dimer in patients with lung cancer (stageⅠ, Ⅱ, Ⅲa) and (Ⅲb, Ⅳ) were significantly higher than those in normal control group (P <0.01) The dimer level was also significantly higher in patients with lung cancer (stage I, II, IIIa) (P <0.01). Conclusion: The determination of plasma D-dimer level has some clinical significance in the diagnosis of lung cancer and the evaluation of the disease.