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氯丁二烯(CH_2=CClCH=CH_2)为氯丁橡胶的单体,氯丁橡胶具有耐油、耐腐蚀、耐老化、不易燃等优点,广泛用于电线、电缆、运输带及各项工业设备中,是国防和经济建设中的重要原料。氯丁二烯为无色透明易挥发具有刺激性臭味的液体,毒性很强,可引起急性及慢性中毒,但其一系列中毒作用尚未完全阐明。为此,我们对氯丁二烯急性中毒后心血管系统的变化、肠管活动以及各重要器管巯基含量测定及相应引起的机能改变和其相互关系进行了实验研究。
Chloroprene (CH_2 = CClCH = CH_2) is a monomer of neoprene. Neoprene has the advantages of oil resistance, corrosion resistance, aging resistance and non-flammability. It is widely used in wires, cables, transportation belts and various industrial equipment China is an important raw material in national defense and economic construction. Chlorinated butadiene is a colorless, transparent volatile irritating odor liquid, highly toxic, can cause acute and chronic poisoning, but its series of toxic effects have not yet been fully elucidated. To this end, we conducted an experimental study of changes in the cardiovascular system after acute poisoning of chloroprene, the activity of the intestine, and the determination of the sulfhydryl groups in each important tube and their corresponding functional changes.