凋亡不同于坏死,它具有特殊的形态和生化代谢的改变。许多因素可诱导细胞凋亡,而辐射致畸不同于一般的生物和化学突变剂,胚胎器官发生时进行宫内照射,可明显增加畸形发生的几率,其机制尚不清楚,为此探讨了辐射诱导的凋亡和肢体畸形发生的关系。方法:室温下对妊娠第11天肢芽形成 Apoptosis is different from necrosis, it has a special morphological and metabolic changes. Many factors can induce apoptosis, and radiation teratogenic different from the general biological and chemical mutagens, intrauterine organ irradiation occurs when the organ may significantly increase the incidence of deformity, the mechanism is unclear, for which the radiation Relationship between induced apoptosis and limb deformity. Methods: The limb bud formation on the 11th day of pregnancy at room temperature