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碱性成纤维细胞生长因子(basic fibroblast growth factor, bFGF)又称为FGF-2,是目前备受关注的亲肝素生长因子家族成员中的一员。它能刺激中胚层及神经外胚层细胞增生,并参与血管新生的过程。虽然已证实在人体的多种体液中存在bFGF,但人的唾液中是否含有bFGF尚不得而知。 众所周知,唾液对于润滑和保护口咽部的软硬组织具有重要作用,而且唾液还能通过减少凝血时间和加速伤口收缩而促进软组织修复。唾液促进伤口愈合的作用,可能与唾液中存在的多种生长因子如EGF,
Basic fibroblast growth factor (bFGF), also known as FGF-2, is a member of the family of heparin growth factors of great interest. It can stimulate mesoderm and neuroectodermal cell proliferation, and participate in the process of angiogenesis. Although bFGF has been shown to exist in various body fluids of the human body, it is not known whether human saliva contains bFGF. It is well-known that saliva plays an important role in lubricating and protecting the soft and hard tissues of the oropharynx, and that saliva also promotes soft tissue repair by reducing clotting time and accelerating wound contractions. The role of saliva in promoting wound healing may be related to the presence of a variety of salivary growth factors such as EGF,