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目的调查本院妇产科围手术期抗菌药物的使用情况,为促进临床合理使用抗菌药物提供参考。方法抽取2010年1-12月妇产科手术病例316例,记录相关内容,根据《抗菌药物临床应用指导原则》、药品说明书及《应用抗菌药物防治外科感染的指导意见》等相关资料,对妇产科围手术抗菌药物的使用进行合理性评价。结果被调查的病例均使用了抗菌药物,共4大类9个品种。药物选择合理率为64.3%,在术前0.5～2h预防给药的有66例(20.9%),术后用药疗程大于3d者有120例(38%),抗菌药物的使用费用所占比例普遍过高。结论本院妇产科围手术期抗菌药物在药物使用率、品种选择、用药时间、药品费用所占比例等方面有待进一步进行干预管理。
Objective To investigate the use of perioperative antibiotics in obstetrics and gynecology department of our hospital to provide reference for the rational use of antibacterials in clinic. Methods A total of 316 cases of obstetrics and gynecology operations from January 2010 to December 2010 were collected and relevant contents were recorded. According to the Guiding Principles of Clinical Application of Antibacterials, the instruction manual of drugs and the Guiding Opinions on Prevention and Surgical Infection with Antibacterials, The rational use of obstetric perioperative antibiotics was evaluated. Results The investigated cases used antimicrobial drugs in 4 categories and 9 varieties. The rational drug selection rate was 64.3%, 66 (20.9%) were prophylactically preoperatively 0.5 to 2 hours, and 120 (38%) were more than 3 days postoperatively. The cost of antimicrobial use was generally high Too high. Conclusion Obstetrics and gynecology perioperative antibacterial drugs in the drug use rate, variety selection, medication time, the proportion of drug costs and other aspects of the need for further intervention management.