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The origin of 5-HMF (5-hydroxymethyl-2-furaldehyde) in a Shengmaiyin decoction was investigated by the RP-HPLC method below. A C18 column (250 mm×4.6 mm, i.d. 5 μm) with a column temperature of 25 ℃ was used. The mobile phase was a mixture of ultra-p