目的:探讨以消化道症状为首发表现的艾滋病病例特点,提高对艾滋病的认识。方法:回顾性分析3例消化道症状突出的艾滋病的临床表现和实验室检查。结果:3例患者均因配偶有吸毒或不洁性生活史感染,均有消瘦、乏力、食欲减退,其中真菌性食道炎2例,肠道肿瘤1例,发热、咳嗽1例。结论:消化道症状突出的艾滋病的临床表现具有多样性,本组病例以夫妻之间性接触感染为主。有必要在消化内镜检查前对被检查者进行HIV初筛普查。 Objective: To explore the characteristics of AIDS cases with gastrointestinal symptoms as the first manifestation and to raise awareness of AIDS. Methods: Retrospective analysis of 3 cases of gastrointestinal symptoms of prominent AIDS clinical manifestations and laboratory tests. Results: All the 3 patients were infected with drugs or unclean sex history due to spouse’s infection. All of them had weight loss, fatigue and loss of appetite. Among them, 2 were fungal esophagitis, 1 was intestinal tumor, 1 was fever and cough. Conclusion: The clinical manifestations of AIDS with prominent gastrointestinal symptoms are diverse. In this group of patients, the sexual contact infection between husband and wife is the main factor. It is necessary to digest the endoscopy before the subjects were HIV screening screening.