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为了解苯乙烯在人体内的代谢动力学,本文观察了在模拟苯乙烯工作现场中自由活动8小时的志愿者,定时采样分析呼出气中的苯乙烯及随尿排出的苯乙烯代谢产物,经拟会处理实验数据。(1)人吸入40mg/m~3苯乙烯后,呼出的苯乙烯呈三室开放模型。苯乙烯在体内的吸收、分布速度较快,速度常数分别为5.56h~(-1)和0.66h~(-1);苯乙烯一经
In order to understand the pharmacokinetics of styrene in the human body, we observed volunteers who were free to move for 8 hours on the simulated styrene working site, regularly sampling and analyzing the styrene in the expired air and the styrene metabolites excreted in urine Will deal with the experimental data. (1) After inhalation of 40mg / m ~ 3 of styrene, exhaled styrene showed a three-compartment open model. The absorption and distribution speed of styrene in the body are very fast with the rate constants of 5.56h ~ (-1) and 0.66h ~ (-1), respectively. Styrene