以Ｃ１８（５～１０μｍ）为填充剂，用乙腈水或乙腈水甲醇磷酸为流动相进行环孢素胶丸的含量测定，均能获得满意的结果。回收率分别为９９．６６％、９９．７１％，标准偏差分别为０．３４％、０．４２％，相对标准差分别为０．３４％、０．４２％。方法具有良好的通用性和准确性。并以Ｓａｎｄｏｚ公司产品和华东公司产品为样品，同时用美国药典（２３版）的方法进行对照试验，平均相对偏差分别为０．２２％、０．３５％ C18 (5 ~ 10μm) as a filler, with acetonitrile or water methanolic acetonitrile as the mobile phase cyclosporin capsule content determination, can get satisfactory results. The recoveries were 99.66% and 99.71%, respectively. The standard deviations were 0.34% and 0.42%, respectively. The relative standard deviations were 0.34% and 0.42% respectively. The method has good versatility and accuracy. The Sandoz and East China products were used as samples, and the control experiments were conducted by the method of the United States Pharmacopeia (version 23) with the average relative deviations of 0.22% and 0.35%