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目的:为比较剖宫产术前和术后预防性抗生素用药方案。方法:对100例足月妊娠需要剖宫产结束分娩的孕妇,按入院顺序随机分为术前用药(实验组),术后用药(对照组)两组,使用氨苄西林/舒巴坦3g,观察术后体温、并发症、腹部切口愈合等指标,比较两组抗生素用量和疗效。结果:两组均有明显疗效,而实验组对降低术后3天体温升高更有效(P<0.05),并发尿路感染各1例、腹部切口感染对照组1例,无统计学意义。每人用药总量实验组少(P<0.05)。结论:剖宫产术前预防性抗生素使用比术后用药疗效较好,费用降低。
Objective: To compare preoperative and postoperative prophylactic antibiotic regimens for cesarean section. Methods: 100 pregnant women who needed cesarean delivery after full-term pregnancy were randomly divided into preoperative medication (experimental group) and postoperative medication (control group), ampicillin / sulbactam 3g, Observed postoperative body temperature, complications, abdominal incision healing and other indicators, the two groups compared the amount of antibiotics and efficacy. Results: The two groups had significant curative effect, while the experimental group was more effective in reducing body temperature 3 days after operation (P <0.05), one case of urinary tract infection and one case of abdominal incision infection control group, which had no statistical significance. The total amount of medication per person experimental group less (P <0.05). Conclusion: Pre-operative antibiotic prophylaxis before cesarean section has better curative effect and lower cost than postoperative medication.