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目的探讨益生菌对小儿特异反应性疾病早期预防的影响。方法选取在广东省惠州市中心人民医院出生的164例新生儿,将其资料按随机数字表法分为观察组与对照组,各82例。观察组新生儿口服双歧杆菌三联活菌散,对照组新生儿给予安慰剂,比较两组新生儿特异反应性疾病的发生情况。结果观察组新生儿特异反应性疾病的发病率为22.0%,明显低于对照组的47.6%,差异有统计学意义(P<0.05)。结论及时服用益生菌能够对特异反应性疾病起到有效的预防作用。
Objective To investigate the effect of probiotics on the early prevention of pediatric specific reactivity diseases. Methods A total of 164 newborns were enrolled in the People ’s Hospital of Huizhou, Guangdong Province. Their data were divided into observation group and control group by random number table method, with 82 cases in each group. The newborns in the observation group were given oral Bifidobacterium triple viable bacteria, and the control group was given placebo. The incidence of neonatal specific reactivity was compared between the two groups. Results The incidence of neonatal atopic dermatitis in observation group was 22.0%, which was significantly lower than that in control group (47.6%) (P <0.05). Conclusions The timely administration of probiotics can effectively prevent specific reactive diseases.