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目的观察甲钴胺治疗糖尿病足下肢神经病变的临床疗效。方法将58例确诊为糖尿病足的患者随机分为两组。其中对照组26例,采用常规治疗方法;治疗组32例,采用甲钴铵肌肉注射治疗。观察两种方法治疗的效果。结果治疗组患者的感觉异常、肌无力及萎缩情况、腱反射反应,以及肌电图测神经传导速度较对照组有明显改善。且就总有效率相比,对照组26例,总有效率57.7%;治疗组32例,总有效率90.1%。治疗组明显高于对照组。结论甲钴胺治疗糖尿病足下肢神经病变较常规治疗方法有更明显的疗效。
Objective To observe the clinical efficacy of mecobalamin in the treatment of diabetic lower extremity neuropathy. Methods Fifty-eight patients with diabetic foot were randomly divided into two groups. The control group of 26 cases, using conventional treatment methods; treatment group of 32 cases, the use of methylcobalamin intramuscular injection therapy. Observed the effect of two methods of treatment. Results The patients in the treatment group had sensory abnormalities, weakness and atrophy, tendon reflexes, and nerve conduction velocity measured by electromyography significantly improved compared with the control group. Compared with the total effective rate, the control group of 26 patients, the total effective rate was 57.7%; the treatment group of 32 patients, the total effective rate was 90.1%. The treatment group was significantly higher than the control group. Conclusion Mecobalamin treatment of diabetic lower extremity neuropathy than the conventional treatment methods have a more significant effect.