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新发现的组胺受体分析组胺对人血小板摄入5-羟色胺的作用后,发现血小板上的H_2受体与至今已了解的H_2受体不同。H_2拮抗药抑制组胺对血小板的作用的浓度,为抑制胃酸分泌的浓度的1/10～1/100。即使让组胺作用,血小板的cAMP水平也不变,仅伴有cGMP上升。一般认为这是H_2受体的亚型,称为H_(2h)受体。也有报告认为中枢神经系统中存在着与其他部位效应不同的亚型。
New Histamine Receptors Analysis of histamine on human platelets uptake of serotonin, and found that the platelet H_2 receptor with the H 2 receptor has been known to be different. The concentration of H 2 antagonist inhibiting the action of histamine on platelets is 1/10 to 1/100 of the concentration that inhibits gastric acid secretion. Even if the role of histamine, platelet cAMP levels are unchanged, only associated with cGMP increased. It is generally believed that this is a subtype of H 2 receptor called the H 2 (2h) receptor. There are also reports that there are subtypes of CNS that have different effects from other sites.