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氟苯咪唑是一种甲苯咪唑的对氟类似物。一些动物的胃肠道对该化合物有较好的耐受性,且该药有较好的抗线虫作用。本文评价不同剂量、疗程的氟苯咪唑治疗鞭虫和蛔虫病患者的疗效。用氟苯咪唑治疗的对象为印度小学生,年龄6～12岁,体重在10kg以上,在治前3个月未服过任何驱肠虫药。用200mg、500mg、600mg各1次和300mg每天1次,连服2天4种剂量疗法分别治疗了42、52、32和43例鞭虫病人和40、47、33和34例蛔虫病人。各治疗组于治毕后4周粪检排出的虫卵数,根据患者虫卵减少率和全愈率评价
Fluoribezole is a p-fluoro analog of mebendazole. The gastrointestinal tract of some animals is well tolerated by the compound, and the drug has good resistance to nematodes. This article evaluates the efficacy of different doses and courses of flubendazole in patients with whipworm and ascariasis. Flubendazole was used for treatment of primary school students in India, aged 6 to 12 years old, weighing 10kg or more, 3 months before treatment did not take any anthelmintics. Forty-two, 52, 32 and 43 cases of whipworm and 40, 47, 33 and 34 cases of roundworms were treated with 200 mg, 500 mg, 600 mg, and 300 mg once daily for 4 days with 2 doses of 2 doses each. In each treatment group, the number of eggs excreted in fecal examination 4 weeks after the treatment was evaluated according to the reduction rate and the complete cure rate