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对高促性腺激素组(高Gn)32例,低促性腺激素组(低Gn)27例,分别测定血液流变学及性激素.结果:两组全血低切粘度(ηb40~(s-1))、血浆粘度(ηp)、还原粘度(ηr)、k值、体外血栓长度(L)、湿重(MW)与对照组比较均有非常显著差异.高Gn组促卵泡成熟激素(FSH)、黄体生成激素(LH)均显著增高,低Gn组FSH、LH均显著下降.两组雌二醇(E_2)催乳素(PRL)均下降,睾酮(T)变化不大.指出高Gn、低Gn闭经妇女尽管闭经的原因不同,但最终均可造成体内E_2水平低落及血液流变学高粘性的改变.提示:对闭经妇女存在的高粘血症应引起临床重视,且血液流变学检查为其早期诊断及疗效的观察提供了客观依据.
32 cases of high gonadotropin group (high Gn) and 27 cases of low gonadotropin group (low Gn) were measured for hemorheology and sex hormones.Results: The low blood viscosity (ηb40 ~ (s-1 ), Plasma viscosity (ηp), reducing viscosity (ηr), k value, in vitro thrombus length (L), wet weight (MW) were significantly different compared with the control group.High follicle stimulating hormone (FSH) , LH (LH) were significantly increased, while FSH and LH in low Gn group were significantly decreased.The levels of prolactin (PRL) in both groups decreased but testosterone (T) changed little.The high Gn, low Gn amenorrhea women despite the different causes of amenorrhea, but eventually can cause lower E_2 levels in vivo and hematological rheumatic hyperviscosity changes. Tip: hyperviscosity of amenorrhea women should pay attention to the clinical and hemorheological examination For its early diagnosis and efficacy of observation provides an objective basis.