Scaffold proteins are known to play critical roles in very diverse cellular processes including trafficking, anchoring and clustering of ion channels/receptors;
Bacterial pathogens inject virulent effector proteins into host cells to inhibit or manipulate host cellular processes.We previous demonstrates that these effec
The proteasomal ATPase ring, comprising Rpt1-Rpt6, associates with the heptameric α ring of the proteasome core particle (CP) in the mature proteasome, with th
Metabolic homeostasis is maintained by various cellular sensors, including the master kinases AMPK(AMP-activated protein kinase) and mTORC 1.In response to low
The role of the small GTPase Ran in spindle assembly has been recently uncovered to ensure the correct chromosome segregation and thus genetic stability in mamm