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本文报告用顺铂加足叶乙甙联合腹腔内灌注,治疗恶性腹水16例,显效7例(43.8％),有效5例(31.3％),总有效率为75.0％(12/16).其中胃癌10例中9例有效.毒性反应主要为少数病人有轻度恶心、呕吐、骨髓抑制很轻微,未发现局部毒副作用.认为该疗法对晚期癌症病人并发恶性腹水者安全有效.
In this report, 16 patients with malignant ascites were treated with cisplatin, euphorbia, and intraperitoneal perfusion. Seven cases (43.8%) were markedly effective, five cases (31.3%) were effective, and the total effective rate was 75.0% (12/16). Of the 10 cases of gastric cancer, 9 cases were effective. The toxicity was mainly due to mild nausea, vomiting, and slight bone marrow suppression in a small number of patients. No side effects were found. It is considered that this therapy is safe and effective for advanced cancer patients with malignant ascites.