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用RP－HPLC法测定了复方醋酸泼尼松搽剂中醋酸泼尼松的含量。采用Shim－PackCLCODSC18（150mm×6．0－，5μm），以甲醇-水（65：35）为流动相，能使醋酸泼尼松峰得到很好的分离，呈良好的线性关系（r=0．99999），平均回收率为100．31％，RSD为0．73％。
The content of prednisone acetate in compound prednisone acetate was determined by RP-HPLC. Using Shim-Pack CLCODSC18(150mm×6.0-,5μm) and methanol-water(65:35) as mobile phase, the prednisone peak can be well separated, showing a good linear relationship (r=0. 99999), the average recovery rate was 100.31%, and the RSD was 0.73%.