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睾酮是一种雄激素,近年发现血管内皮细胞及平滑肌细胞有雄激素受体表达,提示睾酮对血管功能有调节作用。睾酮可影响血压;可通过内皮依赖或内皮非依赖的方式扩张血管;可直接作用于血管平滑肌细胞上的钾通道及钙通道引起血管舒张;另外还可参与调节血管局部炎症反应。然而,睾酮对血管的作用是复杂的,需要进一步研究加以证实。
Testosterone is an androgen, in recent years found that vascular endothelial cells and smooth muscle cells have androgen receptor expression, suggesting that testosterone has a regulatory effect on vascular function. Testosterone can affect blood pressure; dilation of blood vessels by endothelium-dependent or endothelium-independent; can directly affect the potassium channels and calcium channels on vascular smooth muscle cells cause vasodilatation; in addition can also be involved in the regulation of vascular local inflammatory response. However, the effect of testosterone on blood vessels is complex and needs further study to confirm.