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对６３例接受顺铂和／或阿霉素联合化疗患者进行了随机自身对照，观察康泉和枢复宁预防抗癌药物引起恶心、呕吐的效果。患者均在ｄ１给药。６３例患者被随机分为Ａ，Ｂ两组，接受２个周期相同方案的化疗。Ａ组第１周期用康泉（格雷西隆）止吐，第２周期用枢复宁（奥坦西隆）止吐；Ｂ组第１周期用枢复宁止吐，第２周期用康泉止吐。结果表明：康泉ｄ１止吐的有效率为９０．５％，平均呕吐为４次。枢复宁ｄ１止吐有效率为８２．３％，平均呕吐次数为４．６次。统计学两组无显著差异。对迟发性呕吐和副作用也进行对比，康泉与枢复宁也无明显差别。
Sixty-three patients receiving cisplatin and / or doxorubicin combined with chemotherapy were randomized to observe the effects of Kangquan and Shufunning on preventing nausea and vomiting caused by anticancer drugs. Patients were given d1. Sixty-three patients were randomized to A and B groups to receive chemotherapy in two cycles of the same protocol. A group of the first cycle of Kang Quan (Gracilan) antiemetic, the second cycle of the use of Zufu Ning (OTC tamsulosin) antiemetic; the first cycle of Group B with Shudu Ning antiemetic, the second cycle of Kang Quan Antiemetic The results showed that: Kangquan d1 antiemetic efficiency was 90.5%, the average vomiting was 4 times. Shu-Fu Ning d1 antiemetic efficiency was 82.3%, the average number of vomiting 4.6 times. There was no significant difference between the two groups in statistics. Delayed vomiting and side effects were also compared, Kang Quan and Shu Fu Ning also no significant difference.