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为研究高温复合电离辐射对小鼠早期的胚胎效应，选用以孕 ９ｄ ＬＡＣＡ小鼠，给予 ４２℃ １０ｍｉｎ１．０Ｇｙ ６０Ｃｏ γ射线处理。于孕后第 １８天取出胎鼠，观察生长发育情况，测量脑 ＤＮＡ、 ＲＮＡ、蛋白质含量。结果显示，与对照组相比 １．０Ｇｙ胚鼠组发育迟缓；核酸、蛋白质含量明显下降，而 ４２℃组变化不显著， ４２℃＋１．０Ｇｙ照射组损伤程度介于 ４２℃组与 １．０Ｇｙ组之间。这表明 １．０Ｇｙ ６０Ｃｏ γ线使胎鼠生长发育受到影响。而预先 ４２ ℃ １０ｍｉｎ处理孕鼠；其胎仔对随后较大剂量电离辐 射打击表现出交叉适应性反应。
In order to study the early embryonic effects of high-temperature compound ionizing radiation on mice, 9-L pregnant LACA mice were given 10 min1.0Gy 60Co γ-rays treatment at 42 ℃. On the 18th day after pregnancy, the fetus was taken out to observe the growth and development, and the brain DNA, RNA and protein contents were measured. The results showed that compared with the control group, the 1.0Gy embryos developed slowly and the contents of nucleic acid and protein decreased significantly, while the changes at 42 ℃ were not significant. The damage degree at 42 ℃ and 1.0Gy was between 42 ℃ and 1.0Gy Between groups. This shows that the 1.0Gy 60Co γ-ray to affect the growth and development of fetal rats. However, the pregnant rats were pretreated at 42 ℃ for 10 min, and their fetuses showed cross-adaptive response to the subsequent larger doses of ionizing radiation.