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采用逆转录套式聚合酶链反应法（ Ｒ Ｔ－ ｎ Ｐ Ｃ Ｒ） 检测各型肝病患者血清中 Ｈ Ｇ Ｖ Ｒ Ｎ Ａ。结果８０ 例各型肝病患者中， Ｈ Ｇ Ｖ Ｒ Ｎ Ａ 阳性率为１６２５ ％ （１３／８０） ，其中乙型肝炎肝硬变、慢性乙型和慢性丙型肝炎的 Ｈ Ｇ Ｖ Ｒ Ｎ Ａ 阳性率分别为３３３３ ％ 、２６０９ ％ 和２０００ ％ ，均显著高于急性肝炎（８３３ ％ ， Ｐ＜ ００５） ；急性和慢性非甲～戊型肝炎的 Ｈ Ｇ Ｖ Ｒ Ｎ Ａ 阳性率分别为２３０８ ％ 和３３３３ ％ ；各型肝病患者中， Ｈ Ｇ Ｖ Ｒ Ｎ Ａ 阳性和阴性组的 Ａ Ｌ Ｔ、 Ａ Ｓ Ｔ 和 Ｓ Ｂ 水平均无显著性差异；各型乙肝患者中， Ｈ Ｇ Ｖ Ｒ Ｎ Ａ 阳性和阴性组的 Ｈ Ｂｓ Ａｇ 、 Ｈ Ｂｅ Ａｇ 和 Ｈ Ｂ Ｖ Ｄ Ｎ Ａ 的阳性率也无显著性差异，表明在宜昌地区存在 Ｈ Ｇ Ｖ 感染； Ｈ Ｇ Ｖ 与 Ｈ Ｂ Ｖ 和 Ｈ Ｃ Ｖ 合并感染较为常见，合并感染 Ｈ Ｇ Ｖ并不加重肝损害程度， Ｈ Ｇ Ｖ 合并感染 Ｈ Ｂ Ｖ 时，对 Ｈ Ｂ Ｖ 复制无影响。
HG V R N A was detected in sera of patients with various liver diseases by reverse transcription-polymerase chain reaction (RT-PCR). Results The positive rate of HG V R N A was 1625% (13/80) in 80 cases of various liver diseases. Among them, H G V R N of cirrhosis of hepatitis B, chronic hepatitis B and chronic hepatitis C A positive rates were 3333%, 2609% and 2000%, respectively, which were significantly higher than those of acute hepatitis (833%, P <005). The positive rates of H The positive rates of G V R N A were 2308% and 3333% respectively. There was no significant difference in A L T, A S T and S B between HG V R N A positive and negative groups There was no significant difference in the positive rates of H Bs Ag, H Be Ag and H B V D N A between HG V R N A positive and negative groups in all types of hepatitis B patients, indicating that H G V infection; H G V infection with H B V and H C V infection is more common, combined with H G V infection does not increase the degree of liver damage When infection H G V H B V, H B V had no effect on replication.