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目前认为,胸腺切除术后治疗重症肌无力最有效的方法之一是长期隔日口服肾上腺皮质类固醇.然而其缺点是某些病人可出现类固醇依赖倾向及不同类型的副作用.为此,本研究选择类固醇依赖性重症肌无力患者,施行间歇性、单剂量类固醇口服疗法,其疗效与长期隔日疗法者基本相同,而副作用则较少.作者选择3例经长期隔日口服类固醇治疗有效的胸腺切除术后的重症肌无力病人,其病情不易控制,停药后易复发,且已出现类固醇的副作用,如例1有青光眼,例3有满月脸.作者采用逐渐增大强的松龙的剂量的方法,待病情控制后,根据用药日
Currently, one of the most effective methods of treating myasthenia gravis after thymectomy is long-term oral administration of adrenocorticotropic steroids, however, the disadvantage is that some patients may experience steroid-dependent propensity and different types of side effects.To this end, we selected steroids Patients with myasthenia gravis who received intermittent, single-dose oral steroid therapy have similar efficacy and long-term regimens with fewer side effects, and the authors selected 3 patients who had been treated with long-term oral steroids for effective thymectomy Patients with myasthenia gravis, its condition is not easy to control, easy to relapse after stopping, and the side effects of steroids have emerged, such as glaucoma in case 1, full moon face in Example 3. The authors use a gradual increase in the dose of prednisolone to be After the condition is controlled, according to the medication day