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目的:探讨桂枝龙牡汤联合V-C、果糖二磷酸钠治疗心阳不振型小儿心肌炎的临床效果。方法:选取67例小儿心肌炎患儿,随机分为观察组和对照组,观察组34例患儿给予桂枝龙牡汤联合V-C和果糖二磷酸钠治疗,对照组33例患儿给予V-C、果糖二磷酸钠及相应抗感染治疗,比较两组患儿的治疗效果。结果:观察组患儿总有效率为94.1%,明显高于对照组的72.7%,两组患儿总有效率比较差异有统计学意义(P<0.05)。两组患儿治疗前心肌肌钙蛋白I和CK-MB的表达水平比较,差异无统计学意义(P>0.05),治疗后两组患儿心肌肌钙蛋白I和CK-MB水平均较治疗前有所改善,且观察组改善更明显,差异有统计学意义(P<0.05)。结论:桂枝龙牡汤联合V-C、果糖二磷酸钠治疗心阳不振型小儿心肌炎具有较好的临床效果,能有效改善患儿心肌酶的表达情况,值得临床推广应用。
Objective: To investigate the clinical effect of Guizhi Longmu Decoction combined with V-C and sodium fructose diphosphate in the treatment of children with heart-Yang deficiency. Methods: Sixty-seven pediatric children with myocarditis were selected and randomly divided into observation group and control group. In the observation group, 34 cases were treated with Guizhi Longmu Decoction combined with VC and sodium fructose diphosphate. 33 children in the control group were given VC, fructose Diphosphate and the corresponding anti-infective treatment, the treatment effect of two groups of children were compared. Results: The total effective rate in the observation group was 94.1%, which was significantly higher than that in the control group (72.7%). The total effective rate in the two groups was statistically significant (P <0.05). There was no significant difference in cardiac troponin I and CK-MB expression levels between the two groups before treatment (P> 0.05). After treatment, the levels of cardiac troponin I and CK-MB in both groups were significantly higher than those in the treatment group Before the improvement, and the observation group improved more significantly, the difference was statistically significant (P <0.05). Conclusion: Guizhi Longmu Decoction combined with V-C and sodium fructose diphosphate in the treatment of children with cardiomyopathy-positive myocarditis has good clinical effect, which can effectively improve the expression of myocardial enzymes in children and is worthy of clinical application.