在55岁以上的男性中,前列腺癌占癌肿死亡的1/3。在很多患者中用放疗或手术不可能治愈,因仅30％左右的肿瘤局限于前列腺;其余则有广泛的局部病变或远处转移。较为进展性病变的主要症状为流出道梗阻及因转移而引起的骨痛,而70～80%患者可能对内分泌治疗有效。由于主要治疗为姑息性,故对有膀胱流出道梗阻者的开始治疗为作经尿道的切除术,其疗效常较满意,有复发症状者可作内分泌治疗。传统的雌分泌治疗为睾丸切除术或雌激素治疗。目前不赞成雌激素治疗,因其难以被接受,且在此年龄组男 In men over the age of 55, prostate cancer accounts for 1/3 of cancer deaths. It is impossible to cure with radiotherapy or surgery in many patients because only about 30% of tumors are confined to the prostate; the rest are extensive local lesions or distant metastases. The main symptoms of more progressive lesions are obstruction of the outflow tract and bone pain due to metastasis, and 70 to 80% of patients may be effective for endocrine therapy. Since the main treatment is palliative, the initial treatment for patients with bladder outflow tract obstruction for transurethral resection, the efficacy is often more satisfactory, there are recurrent symptoms can be used for endocrine therapy. The traditional estrogen therapy is orchiectomy or estrogen therapy. Estrogen therapy is not currently supported because it is difficult to accept and is in this age group male