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目的探讨替硝唑联合左氧氟沙星治疗盆腔炎的临床疗效。方法选择2014年7月—2015年7月收治的盆腔炎患者106例,根据治疗方法不同分为对照组和观察组,各53例。观察组给予替硝唑联合左氧氟沙星治疗,对照组给予左氧氟沙星联合甲硝唑治疗,比较两组患者治疗前后的C反应蛋白(CRP)水平、临床疗效及不良反应发生情况。结果治疗前两组患者CRP水平比较,差异无统计学意义(P>0.05),治疗后观察组患者CRP水平低于对照组,差异有统计学意义(P<0.05)。观察组总有效率高于对照组,不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论左氧氟沙星联合替硝唑治疗盆腔炎的临床疗效显著,不良反应少,提高了患者的生活质量。
Objective To investigate the clinical effect of tinidazole combined with levofloxacin in the treatment of pelvic inflammatory disease. Methods From July 2014 to July 2015, 106 patients with pelvic inflammatory disease were selected and divided into control group and observation group according to different treatment methods, with 53 cases in each group. The observation group was treated with tinidazole and levofloxacin, while the control group was treated with levofloxacin plus metronidazole. The levels of C-reactive protein (CRP), clinical efficacy and adverse reactions in both groups before and after treatment were compared. Results There was no significant difference in CRP levels between the two groups before treatment (P> 0.05). The CRP level in the observation group was lower than that in the control group after treatment (P <0.05). The total effective rate of the observation group was higher than that of the control group, and the incidence of adverse reactions was lower than that of the control group (P <0.05). Conclusion Levofloxacin combined with tinidazole in the treatment of pelvic inflammatory disease has a significant clinical effect, less adverse reactions, improve the quality of life of patients.