女性在绝经期前心血管病的发病率明显低于男性 ,这在很大程度上是血液中雌激素的作用。一方面 ,雌激素与血管内皮细胞和血管平滑肌细胞内的某种受体结合 ,结合后的复合物改变基因的表达 ,其结果是保护血管免受损伤和减少动脉粥样硬化的发生 ;另一方面 ,雌激素直接作用于血管壁 The incidence of cardiovascular disease in women before menopause is significantly lower than that of men, which is to a large extent the role of estrogen in the blood. On the one hand, estrogen binds to certain receptors in vascular endothelial cells and vascular smooth muscle cells, and the combined complexes alter the expression of genes, the result of which is to protect the blood vessels from damage and to reduce the occurrence of atherosclerosis; Aspects, estrogen directly on the vessel wall