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目的观察肝炎后肝硬化门脉高压性胃病(PHG)患者半固体试餐胃排空变化。方法选择28例PHG患者(PHG组)及15例正常人(对照组)作为研究对象,受检者行99Tcm-DTPA标记的半固体试餐胃排空检测,以单光子发射计算机断层显像获得胃半排空时间(GET1/2)、90min残留率(RR90)等参数。比较PHG患者与正常人胃排空的差异。结果 PHG组GET1/2、RR90明显高于正常对照组,分别为(67.5±15.2)minvs(43.7±7.8)min,(41.0±6.5)%vs(12.0±5.4)%,差异均有统计学意义(P<0.05,P<0.01)。结论 PHG患者半固体食物排空延缓,消化期储留增加。PHG患者胃排空能力减弱可能与动静脉分流、胃肠激素水平异常、自主神经功能障碍有关。
Objective To observe the changes of gastric emptying in semi-solid test in patients with posthepatitic cirrhosis and portal hypertensive gastropathy (PHG). Methods 28 PHG patients (PHG group) and 15 normal controls (control group) were selected as subjects. The subjects were examined by gastric emptying with a semi-solid test labeled with 99Tcm-DTPA and single photon emission computed tomography Gastric emptying time (GET1 / 2), 90min residual rate (RR90) and other parameters. To compare the differences of gastric emptying between PHG patients and normal people. Results The values of GET1 / 2 and RR90 in PHG group were significantly higher than those in control group (67.5 ± 15.2) min vs (43.7 ± 7.8) min and (41.0 ± 6.5)% vs (12.0 ± 5.4)%, respectively (P <0.05, P <0.01). Conclusions Semi-solid food in PHG patients was delayed in emptying and stored in digestive stage. Weak gastric emptying in patients with PHG may be related to arteriovenous shunt, abnormal gastrointestinal hormone levels, autonomic dysfunction.