二甲胺四环素(minocycline),即7—二甲胺—6—去氧—6去甲基四环素,为半合成的四环素衍生物。1966年在美国临床试用有效。Martell及Boothe曾经描述其合成及化学性质,KelJy及Kanegis曾报告用碳标记二甲胺四环索的代谢和组织分布情况,Benitz及其同事曾报告对实验动物的形态学上的影响,Steigbigel及其共事者 Minocycline, a 7-dimethylamine-6-deoxy-6 desmethyltetracycline, is a semisynthetic tetracycline derivative. 1966 clinical trials in the United States effective. Martell and Boothe once described their synthesis and chemistry, and KelJy and Kanegis have reported on the carbon metabolism of DMG tetracyclines and tissue distribution, Benitz and colleagues have reported morphological effects on experimental animals, Steigbigel and Their co-workers