糖皮质激素(以下简称激素)在临床上用于治疗急性呼吸窘迫综合征(ARDS)已有多年,但疗效不一。目前争论的焦点有:ARDS的诱因及发病机制的不同与疗效差异的关系;激素受体水平与功能状态对疗效的影响;下丘脑-垂体-肾上腺轴(HAP)功能状态对激素疗效的影响;激素的给药时机、疗程、剂 Glucocorticoids (hereinafter referred to as hormones) have been used clinically for the treatment of acute respiratory distress syndrome (ARDS) for many years, but with different effects. The current controversy is: the causes of ARDS and the pathogenesis of different differences and efficacy differences; hormone receptor levels and functional status of the effect; Hypothalamic-pituitary-adrenal axis (HAP) functional status of hormone effect; Hormone administration timing, treatment, agent