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肾小管性酸中毒(RTA)是一组以肾小管功能紊乱为主要临床表现的疾病,在肾小管疾病中为常见,亦可继发于其他损害肾小管的疾病。Lighfvood于1936年首次报道,国内1958年开始有报道,近年我国屡有报道,其病因与遗传、感染中毒、免疫性疾病、内分泌疾病、慢活肝等疾病有关[1]。RTA不像肾小球疾病那样,可出现特异或突出的症状,它的临床表现比较复杂,早期常易误诊。现将我们经治的两例继发生Ⅰ型肾小管酸中毒报道如下。
Renal tubular acidosis (RTA) is a group of diseases characterized by renal tubular dysfunction as a major clinical manifestation, common in tubular disease and secondary to other renal tubular damage. Lighfvood first reported in 1936, the country began to have reported in 1958, China has repeatedly reported in recent years, the etiology and genetic, infectious poisoning, immune diseases, endocrine diseases, slow living liver disease [1]. RTA unlike glomerular disease, there may be specific or prominent symptoms, its clinical manifestations are more complex, often misdiagnosed early. Now we have two cases of governance after the occurrence of type Ⅰ renal tubular acidosis reported as follows.